Coronavirus (COVID-19) - Latest Information for Patients and Visitors

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COVID-19-Related Research and Clinical Trials

Information on Ongoing COVID-19-Related Studies

We are running treatment trials for patients with moderate and severe COVID-19, as well as studies evaluating disease prevention and exposure response methods. We recently treated the first U.S. patient in a multi-site clinical trial of gimsilumab for patients with severe COVID-19 and ARDS.

See the full list below and read more about our current research and clinical trials for COVID-19 patients.

For additional information about COVID-19 clinical trials at Temple, please call 215-707-1359 or email breathe@tuhs.temple.edu.

List of COVID-19 Research and Clinical Trials

Expanded Access to INOpulse® Inhaled Nitric Oxide Therapy for Patients with Confirmed or Suspected COVID-19 Who Require Supplemental Oxygen
Investigator: Jeffrey Stewart, MD
View Details >

Healthcare Worker Exposure Response and Outcomes (HERO) Registry
The Healthcare Worker Exposure Response & Outcomes (HERO) Registry is a national clinical research community. It asks healthcare workers across the country to share their experiences, and aims to better understand the impact that the COVID-19 pandemic has on you, your colleagues, family and friends.

The HERO Registry is open to anyone who works in a healthcare setting, including nurses, therapists, physicians, emergency responders, food service workers, environmental service workers, interpreters, and transporters.
Learn More or Sign Up for the Registry >

A Study To Assess The Efficacy And Safety Of Gimsilumab In Subjects With Lung Injury Or Acute Respiratory Distress Syndrome Secondary To COVID-19
Investigator: Gerard Criner, MD
Coordinator: Puja Dubal
View Details >

REGENERON: An Adaptive Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study Assessing Efficacy and Safety of Sarilumab for Hospitalized Patients With COVID-19
TIRB #26863
Investigator: Gerard Criner, MD
View Details >

GILEAD: A Phase 3 Randomized Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants with Moderate COVID-19 Compared to Standard of Care Treatment
TIRB #26858
Investigator: Gerard Criner, MD
View Details >

GILEAD: A Phase 3 Randomized Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants with Severe COVID-19
TIRB #26863
Investigator: Gerard Criner, MD
View Details >

Efficacy And Safety Human Coronavirus Immune Plasma (HCIP) Vs. Control (SARS-CoV-2 Non-Immune Plasma) Among Adults Exposed To COVID-19
Investigator: Mohamed S. Alsammak, MD
Coordinator: Helga Criner, RN
View Details >

Healthcare Worker Exposure Response And Outcomes Of Hydroxychloroquine (HERO-HCQ)
TIRB #26967
Investigator: Nina Gentile, MD; Anuradha Paranjape, MD; and Gustavo Fernandez Romero, MD
Coordinator: Hannah Reimer, RN
View Details >