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There are often no symptoms of mitral valve regurgitation in its early stages. In fact, many older people have mitral prolapse or minor mitral regurgitation (discovered as a murmur with a stethoscope) with no problems or need for worry. As regurgitation or prolapse get worse, it may cause fatigue, shortness of breath, cough, palpitations and excessive urination. Later complications may include lung congestion and/or chest pain, arrhythmias or atrial fibrillation, pulmonary hypertension, blood clots in the lungs, heart valve infection or stroke.