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Lupus Program

Lupus Research and Clinical Trials

The Temple Lupus Program is part of the Lupus Clinical Investigators Network (LuCIN). LuCIN is an academic-based clinical trials network comprised of some of the most prestigious medical research centers and experienced lupus physician-scientists throughout North America.

The Lupus team actively participates in innovative multinational lupus clinical trials, funded by the National Institutes of Health, Lupus Research Alliance and a number of pharmaceutical companies.

Clinical trials provide opportunities for patients to participate in the latest therapies available before they are commercially available. The Temple Lupus Program currently has a number of ongoing clinical trials available for lupus patients.

Ongoing Trials and Research Studies

JBT-101 in Systemic Lupus Erythematosus (SLE)

Overview: The purpose of this study is to evaluate the effectiveness, safety and tolerability of JBT-101 (also known as lenabasum) in the treatment of systemic lupus erythematous.

Protocol: Study ID# DAIT ALE09
Phase: Phase 2
Condition(s): Systemic Lupus Erythematosus, SLE, Lupus
Investigator: Roberto Caricchio, MD
Coordinator: Lynne Kohler

Full Title: A Phase 2, Double-blind, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy, Safety, and Tolerability of JBT-101 in Systemic Lupus Erythematosus (ALE09)

Visit clinicaltrials.gov for full description >

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

Overview: The purpose of this study is to evaluate the efficacy of ustekinumab in participants with active systemic lupus erythematosus (SLE) who have not adequately responded to one or more standard of care treatments.

Protocol: Study ID# CR108440
Phase: Phase 3
Condition(s): Lupus Erythematosus, Systemic
Investigator: Roberto Caricchio, MD
Coordinator: Lynne Kohler

Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Ustekinumab in Subjects With Active Systemic Lupus Erythematosus

Visit clinicaltrials.gov for full description >

Systemic Lupus Erythematosus Biomarker and Therapeutic Target Identification

The purpose of this research is to study gene expression in patients with lupus as compared with patients who are not diagnosed with lupus. The goal is to discover new ways to block processes associated with the development of lupus.

For More Information About Clinical Trials and Research

Contact Lynne Kohler, research clinical coordinator, at lynne.kohler@tuhs.temple.edu or call 267-514-5375 to learn more.

You can also read additional information about clinical trials.

To schedule an appointment with the Lupus Program, request an appointment online or call 800-TEMPLE-MED (800-836-7536).