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Lupus Program

Lupus Research and Clinical Trials

The Temple Lupus Program is part of the Lupus Clinical Investigators Network (LuCIN). LuCIN is an academic-based clinical trials network comprised of some of the most prestigious medical research centers and experienced lupus physician-scientists throughout North America.

The Lupus team actively participates in innovative multinational lupus clinical trials, funded by the National Institutes of Health, Lupus Research Alliance and a number of pharmaceutical companies.

Clinical trials provide opportunities for patients to participate in the latest therapies available before they are commercially available. The Temple Lupus Program currently has a number of ongoing clinical trials available for lupus patients.

Ongoing Trials and Research Studies

Investigational Study to Evaluate Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

Overview: The purpose of this study is to evaluate the safety and effectiveness of BMS-986165 compared with placebo with regard to measures of kidney function in participants with lupus nephritis (LN).

Study #: NCT03943147
Phase: Phase 2
Condition: Lupus Nephritis

Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled Evaluation of the Safety and Efficacy of BMS-986165 With Background Treatment in Subjects With Lupus Nephritis

Visit clinicaltrials.gov for full description >

JBT-101 in Systemic Lupus Erythematosus (SLE)

Overview: The purpose of this study is to evaluate the effectiveness, safety and tolerability of JBT-101 (also known as lenabasum) in the treatment of systemic lupus erythematous.

Protocol: Study ID# DAIT ALE09
Phase: Phase 2
Condition(s): Systemic Lupus Erythematosus, SLE, Lupus
Coordinator: Lynne Kohler

Full Title: A Phase 2, Double-blind, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy, Safety, and Tolerability of JBT-101 in Systemic Lupus Erythematosus (ALE09)

Visit clinicaltrials.gov for full description >

Systemic Lupus Erythematosus Biomarker and Therapeutic Target Identification

The purpose of this research is to study gene expression in patients with lupus as compared with patients who are not diagnosed with lupus. The goal is to discover new ways to block processes associated with the development of lupus.

For More Information About Clinical Trials and Research

Contact Lynne Kohler, research clinical coordinator, at lynne.kohler@tuhs.temple.edu or call 267-514-5375 to learn more.

You can also read additional information about clinical trials.

To schedule an appointment with the Lupus Program, request an appointment online or call 800-TEMPLE-MED (800-836-7536).