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Outlets Highlight New Research from Dr. Walter Koch, Former Graduate Student Dr. Ryan Coleman and Lewis Katz School of Medicine Colleagues on GRK5

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New research published online in the journal Science Signaling shows for the first time in animals that keeping a signaling protein known as G protein-coupled kinase 5 (GRK5) out of the heart cell nucleus can block maladaptive growth of the heart, or cardiac hypertrophy. The findings open avenues for the development of GRK5-based therapies to prevent heart failure. Walter J. Koch, PhD, W.W. Smith Endowed Chair in Cardiovascular Medicine, Professor and Chair of the Department of Pharmacology and Director of the Center for Translational Medicine at the Lewis Katz School of Medicine at Temple University, is the senior investigator on the new study. Dr. Ryan C. Coleman, a former graduate student in the Koch laboratory, is first author on the report. Outlets including Medical Xpress, Scienmag and provided coverage of the research.