Medscape highlighted research presented by Truong-An (Andrew) Ho, MD, a Pulmonary and Critical Care Fellow at the Temple Lung Center, at the ERS Congress, which showed that in patients with chronic obstructive pulmonary disease (COPD) and T2 inflammation treated with biologics, those with improved perimeter-adjusted internal perimeter 10 (Pi10) and airway wall percentage (WA%) on quantitative CT had statistically significant improvements in forced expiratory volume in 1 second (FEV1). Extended follow-up showed a trend toward reduced low attenuation area percentage (%LAA), fewer hospitalizations and fewer mean exacerbations per year, suggesting a longer duration may be needed to detect structural changes induced by biologics that target T2 inflammation.