Healio spoke with Gerard Criner, MD, FACP, FACCP, Director of the Temple Lung Center, who is the global principal investigator for the BREATHE-3 trial, which treated its first patient in August. This multicenter, randomized, interventional, controlled, phase 3 trial hopes to determine the safety and impact of a novel bronchoscopic device on lung function in adults with severe COPD-related emphysema and hyperinflation.