Shameek Gayen, MD, Assistant Professor of Clinical Thoracic Medicine and Surgery at the Lewis Katz School of Medicine at Temple University, provided perspective for a Healio article on a study published in ERJ Open Research. The study found that patients with end-stage chronic obstructive pulmonary disease (COPD) with or without pulmonary hypertension had significantly different clinical, hemodynamic and imaging characteristics from patients with mild COPD with a pulmonary vascular phenotype. Dr. Gayen was not involved in the study.