Medicines that are based on mRNAs and proteins – particularly vaccines and antibodies – are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low cost. Now, researchers at the Lewis Katz School of Medicine at Temple University have discovered a new way to boost protein production in cells by as much as several hundredfold. The findings, published online in the journal Molecular Therapy, could lead to the generation of a universal booster for protein production for the development of bioproducts, drugs and vaccines. Wenhui Hu, MD, PhD, Professor of Cardiovascular Sciences, Pathology and Laboratory Medicine, and Neural Sciences, and Professor in the Center for Metabolic Disease Research at the Katz School of Medicine, is the corresponding author for the research. BioBuzz highlighted the findings.
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