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Coronary calcification is an important indicator of many cardiovascular diseases. The goal is to detect it early and treat it aggressively. There are usually no symptoms when coronary calcification is in its early stages. But as the plaque increases, it can trigger vessel spasm or provide a rough vessel surface where clots form. When this happens, blood supply to organs or tissues can be diminished. This can cause serious problems including angina (chest pain), numbness in the extremities, a decrease in blood pressure and heart attack.