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Temple University Hospital First in World to Offer New truFreeze® Spray Cryotherapy System for Patients with Esophageal Disease

Gastroenterologists at Temple University Hospital are the first in the world to provide the truFreeze® Spray Cryotherapy System for patients suffering from esophageal disease, including Barrett's esophagus and esophageal cancer. This minimally invasive technology involves placing a small catheter in an endoscope to spray extremely cold liquid nitrogen and ablate targeted tissue inside the esophagus.

The truFreeze® Spray Cryotherapy System is a new option for the millions of people who suffer from disorders of the esophagus, the tube that propels food to the stomach.

Michael S. Smith, MD, MBA, Medical Director of Temple's Esophageal Program, performed the hospital's first procedures in early November. "Offering our patients spray cryotherapy in addition to other endoscopic treatments makes Temple a truly comprehensive center for the management of Barrett's esophagus and esophageal cancer," says Dr. Smith. "Having truFreeze® at Temple keeps us on the cutting edge of the treatment of these conditions."

Spray cryotherapy is an outpatient procedure that typically permits patients to quickly resume normal activity. "Our first truFreeze® patients have all reported easy recoveries with minimal discomfort," adds Dr. Smith

How Spray Cryotherapy Works

During the procedure, a physician inserts a long tube with a camera on the end (an endoscope) through the mouth and esophagus to enable viewing of the treatment site. The physician then threads a specialized spray cryotherapy catheter through the endoscope, selects the ablation area and sprays extremely cold (-196°C) liquid nitrogen on the diseased tissue to flash freeze and destroy it. The tissue is allowed to thaw, and the freeze-thaw cycle is typically repeated several times as determined necessary by the physician. This rapid freeze and slow thaw of tissue has been proven to destroy the targeted cells without disturbing the underlying connective tissue, providing a framework for healthy cells to regenerate.

Cryotherapy, the use of extreme cold in medical applications, is a proven therapy that has been used for decades to treat diseased tissue on the skin and many parts of the body. The spray cryotherapy system being utilized at Temple University Hospital is a novel and versatile ablation option because of its touch-less spray application, which enables physicians to address tissue of varied shapes and sizes.

Watch a CBS3 Philadelphia video on the new truFreeze® Spray Cryotherapy System available at Temple.

For more information or to schedule an appointment, call 1-800-TEMPLE-MED (1-800-836-7536).

The truFreeze® Spray Cryotherapy System is manufactured by CSA Medical, Inc. More information about CSA Medical can be found at

Editor's Note: Dr. Smith is a consultant for CSA Medical, Inc.

Date Published: Monday, November 26, 2012

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