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Richard I. Fisher, MD

Specialties

Hematology / Oncology, Oncology

about me
publications
about me
Research Interests
  • Development of novel treatments for non-Hodgkin’s lymphoma and Hodgkin disease
  • Development of prognostic markers for non-Hodgkin’s lymphoma and Hodgkin disease
  • Understanding the immunologic response to non-Hodgkin’s lymphoma and Hodgkin disease
Education
  • Fellow, Oncology, National Cancer Institute, Bethesda, MD, 1975
  • Assistant Resident, Medicine, Massachusetts General Hospital, Boston, MA, 1972
  • MD, Harvard Medical School, 1970
Memberships
  • National Comprehensive Cancer Network (NCCN)
    • Cancer Center Directors
    • Non-Hodgkin's Lymphomas Panel
  • American Association for Cancer Research
  • American College of Physician Executives
  • American Medical Association
  • American Society of Clinical Oncology
  • American Society of Hematology
  • American Association of Immunologists
  • American College of Physicians
  • Association of Subspecialty Professors
  • Central Society for Clinical Research
  • Clinical Immunology Society
  • Chicago Medical Society
  • Chicago Society of Internal Medicine
  • European Society for Medical Oncology
  • Illinois State Medical Society
Awards and Honors
Philadelphia Magazine Top Docs 2018
Medical Oncology
  • Philadelphia Magazine Top Doctors, 2018
  • Best Doctors in America®, Best Doctors Inc., 1999-2016
  • Member, Lymphoma Steering Committee, National Cancer Institute (NCI), 2009-present
  • Member, Board of Scientific Advisors, V Foundation, 2003-present
  • Distinction and HOPE Award, American Cancer Society, 2010
  • Chair, Review Committee, NCI Specialized Programs of Research Excellence (SPORE), 2010
  • Team Science Award, Cytebrine Working Group, 2010
  • Harold Amos Fellow, Dean’s Council, Harvard Medical School, 2010
  • Freundlich Leadership Award, Lymphoma Research Foundation, 2009
  • Davey Memorial Award for Outstanding Cancer Research, University of Rochester Medical Center, 2006
  • Grinberg/Wisch Endowed Visiting Lectureship in Hematology/Oncology, Mount Sinai School of Medicine, 2005
  • Derrick Crowther Lecturer, Cologne, Germany, 2001
  • Member, Honorary Medical Board, Lymphoma Research Foundation of America, 2000-2001
publications
Selected Publications

Press OW, Li HL, Schoder H, Straus DJ, Moskowitz CH, LeBlanc M, Rimsza LM, Bartlett NL, Evens AM, Mittra ES, LaCasce AS, Sweetenham JW, Barr PM, Fanale MA, Knopp MV, Noy A, Hsi ED, Cook JR, Lechowicz MJ, Gascoyne RD, Leonard JP, Kahl BS, Cheson BD, Fisher RI, Friedberg JW. US Intergroup Trial of Response-Adapted Therapy for Stage III to IV Hodgkin Lymphoma Using Early Interim Fluorodeoxyglucose-Positron Emission Tomography Imaging: Southwest Oncology Group S0816. Journal of Clinical Oncology, 34(17):2020-+, 2016. PubMed

Stiff PJ, Unger JM, Cook JR, Constine LS, Couban S, Stewart DA, Shea TC, Porcu P, Winter JN, Kahl BS, Miller TP, Tubbs RR, Marcellus D, Friedberg JW, Barton KP, Mills GM, LeBlanc M, Rimsza LM, Forman SJ, Fisher RI. Autologous Transplantation as Consolidation for Aggressive Non-Hodgkin's Lymphoma. New England Journal of Medicine, 369(18):1681-90, 2013. 

Barrington SF, Mikhaeel NG, Kostakoglu L, Meignan M, Hutchings M, Mueller SP, Schwartz LH, Zucca E, Fisher RI, Trotman J, Hoekstra OS, Hicks RJ, O'Doherty MJ, Hustinx R, Biggi A, Cheson BD. Role of Imaging in the Staging and Response Assessment of Lymphoma: Consensus of the International Conference on Malignant Lymphomas Imaging Working Group. Journal of Clinical Oncology, 32(27):3048-+, 2014. PubMed

Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao WM, Zhang MZ, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu XL, Powell J, Yang YD, Xu WH, Zhao H, Kohlhammer H, Rosenwald A, Kluin P, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Ogwang MD, Reynolds SJ, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pittaluga S, Wilson W, Waldmann TA, Rowe M, Mbulaiteye SM, Rickinson AB, Staudt LM. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature, 490(7418):116-20, 2012.  PubMed

Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, Lister TA. Recommendations for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The Lugano Classification. Journal of Clinical Oncology, 32(27):3059-+, 2014.  PubMed

Ngo, V.N., Young, R.M., Schmitz, R., Jhavar, S., Xiao, W., Kohlhammer, H., Xu, W.,Yang, Y., Zhao, H., Shaffer, A.L., Romesser, P., Wright, G., Powell, J., Rosenwald, A., Muller-Hermelink, H.K., Ott, G., Gascoyne, R.D., Connors, J.M., Rimsza, L.M., Campo, E., Jaffe, E.S., Delabie, J., Smeland, E.B., Fisher, R.I., Braziel, R.M., Tubbs, R.R., Cook, J.R., Weisenburger, D.D., Chan, W.C., and Staudt, L.M. Oncogenically Active MYDSS Mutations in Human Lymphoma. Nature. 470:115-119, 2011.   PubMed

 Davis, R.E; Ngo, V.N; Lenz, G; Tolar, P.; Young, R.; Romesser, P.B.; Kohlhammer, H.; Lamy, L; Zhao, H.; Yang, Y.; Xu, W.; Shaffer, A.L.; Wright, G.; Xiao, W.; Powell, J.; Jiang, J.; Thomas, C.J.; Rosenwald, A.; Ott, G.; Muller-Hermelink, H.K.; Gascoyne, R.D.; Connors, J.M.; Rimsza, L.M.; Campo, E.; Jaffe, E.S.; Delabie, J.; Smeland, E.B.; Fisher, R.I.; Braziel, R.M.; Tubbs, R.R.; Cook, J.R.; Weisenburger, D.D.; Chan, W.C.; Pierce, S.K. and Staudt, L.M. Chronic Active B Cell Receptor Signaling in Diffuse Large B Cell Lymphoma. Nature 463:88-92, 2010. PMC2845535    PubMed

Lenz, G.; Wright, G.; Dave, S.S; Xiao, W.; Powell, J.; Zhao, H.; Xu, W.; Tan, B.; Goldschmidt, N.; Iqbal, J.; Vose, J.; Bast, M.; Fu, K.; Weisenburger, D.D.; Greiner, T.C.; Armitage, J.O.; Kyle, A.; May, L.; Gascoyne, R.D.; Connors, J.M.; Troen, G.; Holte, H.; Kvaloy, S.; Dierickx, D.; Verhoef, G.; Delabie, J.; Smeland, E.B.; Jares, P.; Martinez, A.; Lopez-Guillermo, A.; Montserrat, E.; Campo, E.; Braziel, R.M.; Miller, T.P.; Rimsza, L.M.; Cook, J.; Pohlman, B.; Sweetenham, J.; Tubbs, R.R.; Fisher, R.I.; Hartmann, E.; Rosenwald, A.; Ott, G.; Muller-Hermelink, H.K.; Wrench, D.; Lister, T.A.; Jaffe, E.S.; Wilson, W.H.; Chan, W.C., and Staudt, L.M. for the Lymphoma/Leukemia Molecular Profiling Project. Stromal Gene Signatures in Large B Cell Lymphoma. New England Journal of Medicine. 359: 2313-2323, 2008.    PubMed

Lenz, G.; Wright, G.W.; Emre, T.; Kohlhammer, H.; Dave, S.S.; Davis, R.E.; Carty, S.; Lam, L.T.; Shaffer, A.L.; Xiao, W.; Powell, J.; Rosenwald, A.; Ott, G.; Muller-Hermelink, H.K.; Gascoyne, R.D.; Connors, J.M.; Campo, E.; Jaffe, E.S.; Delabie, J.; Smeland, E.B.; Rimsza, L.M.; Fisher, R.I.; Weisenburger, D.D.; Chan, W.C., and Staudt, L.M. Gene Expression Subtypes of Diffuse Large B cell lymphoma Arise by Distinct Genetic Pathways. Proceedings of the National Academy of Science. 105:135 20-5, 2008    PubMed

Lenz, G.; Davis, R.E.; Ngo, V. U.; Lam, L.; George, T.C.; Wright, G.W.; Dave, S.S.; Zhao, H.; Xu, W.; Rosenwald, A.; Ott, G.; Muller-Hermelink, H.K.; Gascoyne, R.D.; Connors, J.M.; Rimsza, L.M.; Campo, E.; Jaffe, E.S.; Delabie, J.; Smeland, E.B.; Fisher, R.I.; Chan, W.C. and Staudt, L.M. for the Leukemia Lymphoma Molecular Profiling Project. Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma. Science. 319: 1676-1679, 2008. 

Sandeep, D.S., Kai, F., Wright, G.W., Lam, L.T., Kluin, P., Boerma, E., Greiner, T.C., Weisenburger, D.D., Rosenwald, A., Ott, G., Hermelink, H.K., Gascoyne, R.D., Delabie, J., Rimsza, L.M., Braziel, R.M., Grogan, T.M., Campo, E., Jaffe, E.S., Dave, B.J., Sanger, W., Bast, M., Vose, J.M., Armitage, J.O., Connors, J.M., Smeland, E.B., Kvaloy, S., Holte, H., Fisher, R.I., Miller, T.P., Montserrat, E., Wilson, W.H., Bahl, M., Zhao, H., Yang, L., Powell, J., Simon, R., Chan, W.C., Staudt, L.M.: Molecular Diagnosis of Burkitt Lymphoma. N. Engl. J. Med. 354:2431-2442, 2006.

 Dave, S.S., Wright, G., Tan, B, Rosenwald, A., Gascoyne, R.D., Chan. W.C., Fisher, R.I., Braziel, R.M., Rimsza, L.M., Grogan, T.M., Miller, T.P., LeBlanc, M., Greiner, T.C., Weisenburger, D.D., Lynch, J.C., Vose, J., Armitage, J.O., Smeland, E.B., Kvaloy, S., Holte, H. , Delabie, J., Connors, J.M., Lansdorp, P., Ouyang, Q., Lister, T.A., Davies, A.J., Norton, A.J., Muller-Hermelink, H.K., Ott, G., Campo, E., Montserrat, E., Wilson, W.H., Jaffe, E.S., Simon, R., Yang, L.,Powell, J., Zhaol, H., Goldschmidt, N., Chiorazzi, M., Staudt, L.M. Length of survival following the diagnosis of follicular lymphoma is predicted by molecular features of non-malignant tumor infiltrating immune cells. N. Engl. J. Med 351:2159-2169, 2004.

 Rosenwald, A., Wright, G., Leroy, K., Yu, X., Gaulard, P., Gascoyne, R.D., Wing C., Chan, W.C., Zhao, H., Haioun, C., Greiner, T.C., Weisenburger, D.D., Lynch, J.C., Vose, J., Armitage, J.O., Smeland, E.B., Kvaloy, S., Holte, H., Delabie, J., Campo, E., Montserrat, E., Lopez-Guillermo, A., Ott, G., Muller-Hermelink, H.K., Connors, J.M., Braziel, R., Grogan, T.M., Fisher, R.I., Miller, T.P., LeBlanc, M., Chiorazzi, M., Zhao, H., Yang, L., Powell, J., Wilson, W.H., Jaffe, E.S., Simon, R., Klausner, R.D., and Staudt, L.M. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J. Exp. Med. 198:851-862, 2003. PMC2194208    PubMed

Rosenwald, A., Wright, G., Wiestner, A., Chan, W.C., Connors, J.M., Campo, E., Gascoyne, R.D., Grogan, T.M., Muller-Hermelink, H.K., Smeland, E.B., Chiorazzi, M., Giltnane, J.M., Hurt, E.M., Zhao, H., Averett, L., Henrickson, S., Yang, L., Powell, J., Wilson, W.H., Jaffe, E.S., Simon, R., Klausner, R.D., Montserrat, E., Bosch, F., Greiner, T.C., Weisenburger, D.D., Sanger, W.G., Dave, B.J., Lynch, J.C., Vose, J., Armitage, J.O., Fisher, R.I., Miller, T.P., LeBlanc, M., Ott, G., Kvaloy, S., Holte, H., Delabie, J. and Staudt, L.M. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell. 3:185-197, 2003.     PubMed

Rosenwald, A., Wright, G., Chan, W.C., Connors, J.M., Campo, E., Fisher, R.I., Gascoyne, R.N., Konrad Muller-Hermeliuk, H., Smeland, E.R., and Staudt, L.M. The use of molecular profiling to predict survival after chemotherapy of diffuse large B-cell lymphomas. N. Engl. J. Med. 346:1937-1947, 2002.    PubMed

Hasenclever, D., Diehl, V., Armitage, J.O., Assouline, D., Bjorkholm, M., Brusamolino, E., Canellos, G.P., Carde, P., Crowther, D., Cunningham, D., Eghbali, H., Ferme, C., Fisher, R.I., Glick, H.J., Glimelius, B., Gobbi, P.G., Holte, H., Horning, S.J., Lister, T.A., Longo, D.L., Mandelli, F., Polliack, A., Proctor, S.J., Specht, L., Sweetenham, J.W., Hudson, G.V.: A Prognostic Score for Advanced Hodgkin’s Disease. N. Engl. J.Med. 339:1506-1514, 1998.

Miller, T.P., Dahlberg, S., Cassady, J.R., Adelstein,, D.J., Spier, C.M., Grogan, T.M., LeBlanc, M., Carlin, S., Chase, E., and Fisher, R.I.: A randomized trial comparing chemotherapy alone to chemotherapy followed by radiotherapy for localized intermediate and high grade non-Hodgkin’s lymphoma. N. Engl. J. Med. 339:21-25, 1998.  

Shipp, M.A., Harrington, D.P., Anderson, J.R., Armitage, J.O., Bonnadonna, G., Brittinger, G., Cabanillas, F., Canellos, G.P., Coiffer, B., Connors, J.M., Cowan, R.A., Crowther, D., Dahlberg, S.J., Engelhard, M., Fisher, R.I., Insselbrecht, C., Horning, S.J., Lepage, E., Lister, A., Meerwaldt, J.H., Montserrat, E., Nissen, N.I., Oken, M.M., Peterson, B.A., Tondini, C., Velasquez, W.S., and Yeap, B.Y: Development of a predictive model for aggressive lymphoma: The international non-Hodgkin's lymphoma prognostic factors project. N. Engl. J. Med. 329:987-994, 1993. 

Fisher, R.I., Gaynor, E.R., Dahlberg, S., Oken, M.M., Grogan, T.M., Mize, E.M., Glick, J.H., Coltman, C.A., and Miller, T.P.: Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma. N. Engl. J. Med. 328:1002-1006, 1993.   PubMed

offices

Office Locations

Fox Chase Cancer Center

333 Cottman Avenue

Philadelphia, PA 19111

888-369-2427

Office Locations

Fox Chase Cancer Center

333 Cottman Avenue

Philadelphia, PA 19111

888-369-2427