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 597 items in 60 pages

New Research Provides Expanded Insights into the Brain’s Response to Opioids and the Search for a New Class of Painkillers with Fewer Side Effects


(Philadelphia, PA) – Opioids are powerful painkillers that act on the brain, but they have a range of harmful side effects including addiction. Researchers from the Max Planck Institute of Biochemistry in collaboration with researchers from the Medical University of Innsbruck, Austria, University of Innsbruck, and the Lewis Katz School of Medicine at Temple University, have developed a tool that gives deeper insights into the brain’s response to opioids.
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Temple Scientists Eradicate Cancer Cells Through
Dual Targeting of DNA Repair Mechanisms


(Philadelphia, PA) – Proteins commonly known as BRCA – short for BReast CAncer susceptibility gene– serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the BRCA repair system is disabled in cancer cells, the cells simply turn to backup repair mechanisms and adapt to alternative repair pathways, a survival mode that also underlies their ability to evade targeted drug therapies. Now, new research by scientists at the Lewis Katz School of Medicine at Temple University shows that it is possible to eliminate at least two backup repair mechanisms at the same time using two targeted therapies.
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Temple Researchers Successfully Reverse
Cognitive Impairments in Mice with Dementia


(Philadelphia, PA) – Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the way of significant clinical advance. But now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) are breaking through that barrier. They show, for the first time in an animal model, that tau pathology – the second-most important lesion in the brain in patients with Alzheimer's disease – can be reversed by a drug.
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Robert H. Lux, Senior Vice President, Treasurer and Chief Financial Officer of Temple University Health System, Named One of Top “Hospital and Health System CFOs to Know” for 2018


(Philadelphia, PA) – Robert H. Lux, CPA, FHFMA, Senior Vice President, Treasurer and Chief Financial Officer of Temple University Health System, has been named one of this year’s top “150 Hospital and Health System CFOs to Know” by Becker’s Hospital Review.
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Temple Researchers Lead Landmark
Trial Demonstrating Effectiveness of Minimally
Invasive Treatment for Emphysema


(Philadelphia, PA) - Surgery to remove small portions of damaged lung tissue helps some patients with severe emphysema but is invasive and risky. Now, an effective, but safer option – the Zephyr® Endobronchial Valve (Zephyr® EBV®), an endoscopic lung volume reduction therapy manufactured by California-based Pulmonx Corporation – may provide an alternative. In a Temple-led clinical trial known as LIBERATE, implantation of Zephyr® EBV® successfully reduced shortness of breath and improved lung function and quality of life, with benefits lasting at least one-year post-intervention.
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Temple’s Dr. Larry Kaiser and Dr. Verdi DiSesa Named
“Great Leaders in Healthcare” by Becker’s Hospital Review


(Philadelphia, PA) – Larry R. Kaiser, MD, FACS, the Lewis Katz Dean and Professor of Thoracic Medicine and Surgery at the Lewis Katz School of Medicine at Temple University (LKSOM), President and CEO of Temple University Health System (TUHS), and Senior Executive Vice President for Health Affairs at Temple University; and Verdi J. DiSesa, MD, MBA, President & CEO of Temple University Hospital (TUH), Senior Vice Dean for Clinical Affairs and Professor of Surgery at LKSOM, and Chief Operating Officer of TUHS, have been named by Becker’s Hospital Review to its list of “100 Great Leaders in Healthcare” for 2018.
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Elevated Homocysteine Identified as Metabolic Risk Factor for
Neurodegenerative Diseases, Scientists at Temple Report


(Philadelphia, PA) – The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism. Genetic diseases or an imbalanced diet, with too much red meat or deficiencies in B vitamins and folic acid, however, can lead to high homocysteine levels, a condition known as hyperhomocysteinemia. This condition causes considerable harm to the heart but can also affect the brain.
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150 Temple Physicians Named
“Top Doctors” by Philadelphia Magazine


(Philadelphia, PA) – One hundred fifty (150) Temple physicians have been named to Philadelphia magazine’s “Top Doctors” list for 2018. Physicians on the list were nominated by their professional peers and practice at Temple University Hospital, Fox Chase Cancer Center, Jeanes Hospital, Temple University Hospital-Episcopal Campus and in the community as part of Temple Physicians, Inc.
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Temple’s Dr. Walter Koch Receives Prestigious $1 Million AHA
Merit Award to Investigate Molecular Signaling by the Heart


(Philadelphia, PA) – Walter J. Koch, PhD, William Wikoff Smith Endowed Chair in Cardiovascular Medicine, Professor and Chair of Pharmacology and Professor and Director of the Center for Translational Medicine at the Lewis Katz School of Medicine at Temple University, has been selected by the American Heart Association as one of only two innovative researchers to receive the organization’s prestigious Merit Award in 2018. The $1 million award, which will be distributed over five years, will fund translational research into how the heart directs body fat to respond to certain conditions.
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Temple University Hospital Earns “LGBTQ Healthcare Equality Leader” Designation in Human Rights Campaign Foundation’s Healthcare Equality Index


(Philadelphia, PA) – Temple University Hospital has earned the designation of “LGBTQ Healthcare Equality Leader” from the Human Rights Campaign Foundation. The designation was awarded in the 11th edition of the Healthcare Equality Index (HEI), released today.
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